diff --git a/.changeset/clever-tables-bow.md b/.changeset/clever-tables-bow.md
new file mode 100644
index 000000000..6a590d6f1
--- /dev/null
+++ b/.changeset/clever-tables-bow.md
@@ -0,0 +1,5 @@
+---
+'@lion/tabs': patch
+---
+
+Select first not-disabled tab if the first one is disabled.
diff --git a/.changeset/fair-adults-carry.md b/.changeset/fair-adults-carry.md
new file mode 100644
index 000000000..9a30a60b5
--- /dev/null
+++ b/.changeset/fair-adults-carry.md
@@ -0,0 +1,5 @@
+---
+'@lion/tabs': minor
+---
+
+Ensures that disabled tab elements are skipped when navigating a tab list with the keyboard.
diff --git a/docs/components/content/tabs/features.md b/docs/components/content/tabs/features.md
index d4ef4821e..ef34fb835 100644
--- a/docs/components/content/tabs/features.md
+++ b/docs/components/content/tabs/features.md
@@ -38,6 +38,31 @@ export const slotsOrder = () => html`
 `;
 ```
 
+## Disabled tabs
+
+You can disable specific tabs by adding the `disabled` attribute to a tab button.
+
+When using the arrow keys to switch tabs, it will skip disabled tabs, but it will not cycle from last to first or vice versa.
+
+```js preview-story
+export const tabsDisabled = () => html`
+  <lion-tabs>
+    <button slot="tab">tab 1</button>
+    <div slot="panel">panel 1</div>
+    <button slot="tab" disabled>tab 2</button>
+    <div slot="panel">panel 2</div>
+    <button slot="tab" disabled>tab 3</button>
+    <div slot="panel">panel 3</div>
+    <button slot="tab">tab 4</button>
+    <div slot="panel">panel 4</div>
+    <button slot="tab">tab 5</button>
+    <div slot="panel">panel 5</div>
+    <button slot="tab" disabled>tab 6</button>
+    <div slot="panel">panel 6</div>
+  </lion-tabs>
+`;
+```
+
 ## Nesting tabs
 
 You can include tabs within tabs
diff --git a/packages/tabs/src/LionTabs.js b/packages/tabs/src/LionTabs.js
index f2ab0309a..c3d31391e 100644
--- a/packages/tabs/src/LionTabs.js
+++ b/packages/tabs/src/LionTabs.js
@@ -164,6 +164,21 @@ export class LionTabs extends LitElement {
   firstUpdated(changedProperties) {
     super.firstUpdated(changedProperties);
     this.__setupSlots();
+    if (this.tabs[0].disabled) {
+      this.selectedIndex = this.tabs.findIndex(tab => !tab.disabled);
+    }
+  }
+
+  get tabs() {
+    return /** @type {HTMLButtonElement[]} */ (Array.from(this.children)).filter(
+      child => child.slot === 'tab',
+    );
+  }
+
+  get panels() {
+    return /** @type {HTMLElement[]} */ (Array.from(this.children)).filter(
+      child => child.slot === 'panel',
+    );
   }
 
   /** @private */
@@ -186,22 +201,16 @@ export class LionTabs extends LitElement {
   __setupStore() {
     /** @type {StoreEntry[]} */
     this.__store = [];
-    const buttons = /** @type {HTMLElement[]} */ (Array.from(this.children)).filter(
-      child => child.slot === 'tab',
-    );
-    const panels = /** @type {HTMLElement[]} */ (Array.from(this.children)).filter(
-      child => child.slot === 'panel',
-    );
-    if (buttons.length !== panels.length) {
+    if (this.tabs.length !== this.panels.length) {
       // eslint-disable-next-line no-console
       console.warn(
-        `The amount of tabs (${buttons.length}) doesn't match the amount of panels (${panels.length}).`,
+        `The amount of tabs (${this.tabs.length}) doesn't match the amount of panels (${this.panels.length}).`,
       );
     }
 
-    buttons.forEach((button, index) => {
+    this.tabs.forEach((button, index) => {
       const uid = uuid();
-      const panel = panels[index];
+      const panel = this.panels[index];
 
       /** @type {StoreEntry} */
       const entry = {
@@ -235,6 +244,56 @@ export class LionTabs extends LitElement {
     this.__store = [];
   }
 
+  /**
+   * @param {HTMLButtonElement[]} tabs
+   * @param {HTMLButtonElement} currentTab
+   * @param {'right' | 'left'} dir
+   * @returns {HTMLButtonElement|undefined}
+   * @private
+   */
+  __getNextNotDisabledTab(tabs, currentTab, dir) {
+    let orderedNotDisabledTabs = /** @type {HTMLButtonElement[]} */ ([]);
+    const nextNotDisabledTabs = tabs.filter((tab, i) => !tab.disabled && i > this.selectedIndex);
+    const prevNotDisabledTabs = tabs.filter((tab, i) => !tab.disabled && i < this.selectedIndex);
+    if (dir === 'right') {
+      orderedNotDisabledTabs = [...nextNotDisabledTabs, ...prevNotDisabledTabs];
+    } else {
+      orderedNotDisabledTabs = [...prevNotDisabledTabs.reverse(), ...nextNotDisabledTabs.reverse()];
+    }
+    return orderedNotDisabledTabs[0];
+  }
+
+  /**
+   * @param {number} newIndex
+   * @param {string} direction
+   * @returns {number}
+   * @private
+   */
+  __getNextAvailableIndex(newIndex, direction) {
+    const currentTab = this.tabs[this.selectedIndex];
+    if (this.tabs.every(tab => !tab.disabled)) {
+      return newIndex;
+    }
+    if (direction === 'ArrowRight' || direction === 'ArrowDown') {
+      const nextNotDisabledTab = this.__getNextNotDisabledTab(this.tabs, currentTab, 'right');
+      return this.tabs.findIndex(tab => nextNotDisabledTab === tab);
+    }
+    if (direction === 'ArrowLeft' || direction === 'ArrowUp') {
+      const nextNotDisabledTab = this.__getNextNotDisabledTab(this.tabs, currentTab, 'left');
+      return this.tabs.findIndex(tab => nextNotDisabledTab === tab);
+    }
+    if (direction === 'Home') {
+      return this.tabs.findIndex(tab => !tab.disabled);
+    }
+    if (direction === 'End') {
+      const notDisabledTabs = this.tabs
+        .map((tab, i) => ({ disabled: tab.disabled, index: i }))
+        .filter(tab => !tab.disabled);
+      return notDisabledTabs[notDisabledTabs.length - 1].index;
+    }
+    return -1;
+  }
+
   /**
    * @param {number} index
    * @returns {(event: Event) => unknown}
@@ -257,24 +316,32 @@ export class LionTabs extends LitElement {
         case 'ArrowDown':
         case 'ArrowRight':
           if (this.selectedIndex + 1 >= this._pairCount) {
-            this._setSelectedIndexWithFocus(0);
+            this._setSelectedIndexWithFocus(this.__getNextAvailableIndex(0, _ev.key));
           } else {
-            this._setSelectedIndexWithFocus(this.selectedIndex + 1);
+            this._setSelectedIndexWithFocus(
+              this.__getNextAvailableIndex(this.selectedIndex + 1, _ev.key),
+            );
           }
           break;
         case 'ArrowUp':
         case 'ArrowLeft':
           if (this.selectedIndex <= 0) {
-            this._setSelectedIndexWithFocus(this._pairCount - 1);
+            this._setSelectedIndexWithFocus(
+              this.__getNextAvailableIndex(this._pairCount - 1, _ev.key),
+            );
           } else {
-            this._setSelectedIndexWithFocus(this.selectedIndex - 1);
+            this._setSelectedIndexWithFocus(
+              this.__getNextAvailableIndex(this.selectedIndex - 1, _ev.key),
+            );
           }
           break;
         case 'Home':
-          this._setSelectedIndexWithFocus(0);
+          this._setSelectedIndexWithFocus(this.__getNextAvailableIndex(0, _ev.key));
           break;
         case 'End':
-          this._setSelectedIndexWithFocus(this._pairCount - 1);
+          this._setSelectedIndexWithFocus(
+            this.__getNextAvailableIndex(this._pairCount - 1, _ev.key),
+          );
           break;
         /* no default */
       }
@@ -297,6 +364,9 @@ export class LionTabs extends LitElement {
    * @protected
    */
   _setSelectedIndexWithFocus(value) {
+    if (value === -1) {
+      return;
+    }
     const stale = this.__selectedIndex;
     this.__selectedIndex = value;
     this.__updateSelected(true);
@@ -323,16 +393,8 @@ export class LionTabs extends LitElement {
     ) {
       return;
     }
-    const previousButton = /** @type {HTMLElement} */ (
-      Array.from(this.children).find(
-        child => child.slot === 'tab' && child.hasAttribute('selected'),
-      )
-    );
-    const previousPanel = /** @type {HTMLElement} */ (
-      Array.from(this.children).find(
-        child => child.slot === 'panel' && child.hasAttribute('selected'),
-      )
-    );
+    const previousButton = this.tabs.find(child => child.hasAttribute('selected'));
+    const previousPanel = this.panels.find(child => child.hasAttribute('selected'));
     if (previousButton) {
       deselectButton(previousButton);
     }
diff --git a/packages/tabs/test/lion-tabs.test.js b/packages/tabs/test/lion-tabs.test.js
index 7ea9d6d3f..99584f952 100644
--- a/packages/tabs/test/lion-tabs.test.js
+++ b/packages/tabs/test/lion-tabs.test.js
@@ -15,6 +15,8 @@ const basicTabs = html`
     <div slot="panel">panel 2</div>
     <button slot="tab">tab 3</button>
     <div slot="panel">panel 3</div>
+    <button slot="tab">tab 4</button>
+    <div slot="panel">panel 4</div>
   </lion-tabs>
 `;
 
@@ -216,7 +218,7 @@ describe('<lion-tabs>', () => {
       const el = /** @type {LionTabs} */ (await fixture(basicTabs));
       const tabs = el.querySelectorAll('[slot=tab]');
       tabs[0].dispatchEvent(new KeyboardEvent('keyup', { key: 'End' }));
-      expect(el.selectedIndex).to.equal(2);
+      expect(el.selectedIndex).to.equal(3);
     });
 
     it('selects first tab on [arrow-right] if on last tab', async () => {
@@ -254,6 +256,90 @@ describe('<lion-tabs>', () => {
       tabs[0].dispatchEvent(new KeyboardEvent('keyup', { key: 'ArrowLeft' }));
       expect(el.selectedIndex).to.equal(2);
     });
+
+    it('selects next available not disabled tab if first tab is disabled', async () => {
+      const el = /** @type {LionTabs} */ (
+        await fixture(html`
+          <lion-tabs>
+            <button slot="tab" disabled>tab 1</button>
+            <div slot="panel">panel 1</div>
+            <button slot="tab">tab 2</button>
+            <div slot="panel">panel 2</div>
+            <button slot="tab">tab 3</button>
+            <div slot="panel">panel 3</div>
+          </lion-tabs>
+        `)
+      );
+      expect(el.selectedIndex).to.equal(1);
+    });
+
+    it('selects next available not disabled tab on [arrow-right] and [arrow-down]', async () => {
+      const el = /** @type {LionTabs} */ (
+        await fixture(html`
+          <lion-tabs>
+            <button slot="tab">tab 1</button>
+            <div slot="panel">panel 1</div>
+            <button slot="tab" disabled>tab 2</button>
+            <div slot="panel">panel 2</div>
+            <button slot="tab">tab 3</button>
+            <div slot="panel">panel 3</div>
+            <button slot="tab" disabled>tab 3</button>
+            <div slot="panel">panel 3</div>
+          </lion-tabs>
+        `)
+      );
+      const tabs = el.querySelectorAll('[slot=tab]');
+      tabs[0].dispatchEvent(new KeyboardEvent('keyup', { key: 'ArrowRight' }));
+      expect(el.selectedIndex).to.equal(2);
+    });
+
+    it('selects next available not disabled tab on [arrow-left] and [arrow-up]', async () => {
+      const el = /** @type {LionTabs} */ (
+        await fixture(html`
+          <lion-tabs>
+            <button slot="tab">tab 1</button>
+            <div slot="panel">panel 1</div>
+            <button slot="tab" disabled>tab 2</button>
+            <div slot="panel">panel 2</div>
+            <button slot="tab">tab 3</button>
+            <div slot="panel">panel 3</div>
+            <button slot="tab" disabled>tab 3</button>
+            <div slot="panel">panel 3</div>
+          </lion-tabs>
+        `)
+      );
+      el.selectedIndex = 2;
+      const tabs = el.querySelectorAll('[slot=tab]');
+      tabs[2].dispatchEvent(new KeyboardEvent('keyup', { key: 'ArrowLeft' }));
+      expect(el.selectedIndex).to.equal(0);
+    });
+
+    it('cycles through tabs even if the last or first tabs are disabled', async () => {
+      const el = /** @type {LionTabs} */ (
+        await fixture(html`
+          <lion-tabs>
+            <button slot="tab" disabled>tab 0</button>
+            <div slot="panel">panel 0</div>
+            <button slot="tab">tab 1</button>
+            <div slot="panel">panel 1</div>
+            <button slot="tab">tab 2</button>
+            <div slot="panel">panel 2</div>
+            <button slot="tab" disabled>tab 3</button>
+            <div slot="panel">panel 3</div>
+          </lion-tabs>
+        `)
+      );
+      const tabs = el.querySelectorAll('[slot=tab]');
+      el.selectedIndex = 1;
+
+      // 0 is disabled, same for 3, so should go to 2
+      tabs[1].dispatchEvent(new KeyboardEvent('keyup', { key: 'ArrowLeft' }));
+      expect(el.selectedIndex).to.equal(2);
+
+      // 3 is disabled, same for 0, so should go to 1
+      tabs[2].dispatchEvent(new KeyboardEvent('keyup', { key: 'ArrowRight' }));
+      expect(el.selectedIndex).to.equal(1);
+    });
   });
 
   describe('Content distribution', () => {
@@ -276,12 +362,12 @@ describe('<lion-tabs>', () => {
       const selectedTab = Array.from(el.children).find(
         child => child.slot === 'tab' && child.hasAttribute('selected'),
       );
-      expect(selectedTab && selectedTab.textContent).to.equal('tab 5');
+      expect(selectedTab && selectedTab.textContent).to.equal('tab 6');
 
       const selectedPanel = Array.from(el.children).find(
         child => child.slot === 'panel' && child.hasAttribute('selected'),
       );
-      expect(selectedPanel && selectedPanel.textContent).to.equal('panel 5');
+      expect(selectedPanel && selectedPanel.textContent).to.equal('panel 6');
     });
   });